ART-TREATED PATIENTS EXHIBIT AN ADAPTIVE IMMUNE RESPONSE AGAINST THE HFVAC PEPTIDES, A POTENTIAL HIV-1 THERAPEUTIC VACCINE (PROVIR/LATITUDE45 STUDY)

ART-Treated Patients Exhibit an Adaptive Immune Response against the HFVAC Peptides, a Potential HIV-1 Therapeutic Vaccine (Provir/Latitude45 Study)

We proposed a new HIV-1 therapeutic vaccine based on conserved cytotoxic T lymphocyte (CTL) OREGA ARCTIC MINT epitopes of archived HIV-1 DNA according to their affinity to the dominant HLA-A and -B alleles of the population investigated.Our proposal (Hla Fitted VAC, HFVAC) was composed of 15 peptides originating from the RT, gag and nef parts of pr

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Inhibition of DYRK1B suppresses inflammation in allergic contact dermatitis model and Th1/Th17 immune response

Abstract Allergic contact dermatitis (ACD) is a type IV hypersensitivity mainly Accessories mediated by Th1/Th17 immune response.Topical corticosteroid is currently the first-line treatment for allergic contact dermatitis (ACD) and systemic administration of immunosuppressive drugs are used in patients with severe disseminated cases.However, increa

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